Adapalene and clindamycin phosphate gel buy online

What is Clindamycin Gel?

Clindamycin phosphate gel is a topical antibiotic that decreases the number of acne lesions, pimples, and comedones. It works by stopping the growth of bacteria that cause acne.

• How to use
• Dosage
• Benefits
• Side effects

How to use Clindamycin phosphate gel

Clindamycin is super easy to use!

Simply clean with a gentle soap the affected area by acne and make sure to completely dry it.

Apply a small amount of the gel on the treated area, rubbing it in gently on the skin before bedtime.

Clindamycin phosphate lotion contains cetostearyl alcohol (2.5%); glycerin; glyceryl stearate SE (with potassium monostearate); isostearyl alcohol (2.5%); methylparaben (0.3%); sodium lauroyl sarcosinate; stearic acid; and purified water.

Clindamycin phosphate gel Benefits

• Treats Acne
• Reduces Inflammation
• Reduces Bacterial Growth
• Helps prevent future eruptions

Clindamycin phosphate gel side effects

The risks are very low, but some women have experienced unwanted side effects when using Clindamycin phosphate. Minor ones include skin dryness, itching, redness, mild burning, or worsening of acne. Those effects will decrease with continued use of the medication.

If you experience blistering, severe burning/swelling of the skin, eye redness and watering (conjunctivitis), eyelid swelling, or skin discoloration, STOP the medication and tell your doctor immediately. Also, rarely this medication can cause discoloration of the skin. Dark-skinned people may notice a lightening in skin color in the area where you use this medication.

The chances of serious side effects are extremely unlikely, but STOP the medication and seek immediate medical attention (call 911 or go to the ER) if you experience any of the following symptoms: severe dizziness, rash, itching/swelling (especially of the face/tongue/throat), trouble breathing.

Frequently Asked Questions

WHAT IS CLINDAMYCIN GEL USED FOR?

Clindamycin Gel is used to stop bacteria from growing and are prescribed to help treat mild to severe acne. It also helps with decreasing inflammation.

HOW TO USE CLINDAMYCIN PHOSPHATE GEL?

First, clean the acne-affected area with a gentle soap and make sure it is completely dry. Apply a small amount of the clindamycin gel or lotion on the treated area, rubbing it in gently on the skin before bedtime.

HOW MUCH IS CLINDAMYCIN GEL?

If you use insurance, then the price will depend on your coverage. If you are paying out of pocket, the price is $55 for a tube.

HOW LONG DOES CLINDAMYCIN SIDE EFFECTS LAST?

If any side effect is experienced while using clindamycin lotion or gel, they should go away after stopping its use. Always contact your doctor if you experience any side effects. And call 911 or go to the ER if you experience any difficulty breathing, itchy rash, etc.

WHAT KIND OF INFECTIONS DOES CLINDAMYCIN TREAT?

Clindamycin topical lotion is used to stop bacteria from growing and is prescribed to help treat mild to severe acne. It also helps with decreasing inflammation.

Clindamycin by mouth or intravenously is also used to treat other infections in internal organs, female reproductive organs and lungs.

WHERE TO BUY CLINDAMYCIN PHOSPHATE TOPICAL GEL?

You can get Clindamycin Phosphate Topical gel pretty much at any pharmacy but you will need a prescription for it because it is only sold under prescription in the USA. Pandia Health’s expert Doctors are happy to help you get a prescription for the most suitable acne treatment for you.

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Brief Summary:

This is a study to see if Adapalene-Clindamycin Combination Gel is effective and safe in the treatment of acne vulgaris, compared to adapalene gel alone and clindamycin gel alone. Adapalene and clindamycin have been reported to have a better effect in acne treatment when used together. This new formulation is also easier to use as it combines two products into a single gel and only needs to be used once a day.

Resource links provided by the National Library of Medicine

Primary Outcome Measures :

1. Percentage Change From Baseline in Total Lesion Counts [ Time Frame: Week 12 ]

   Percent change from Baseline in total lesions counts in each treatment group at Week 12.

   
   
2. Proportion of patients who has at least a two-point reduction in Investigator Global Assessment (IGA) compared to baseline [ Time Frame: Week 12 ]
   

Secondary Outcome Measures :

1. Percentage change from baseline in inflammatory lesion counts [ Time Frame: Week 12 ]

   Percent change from baseline in inflammatory lesions count in each treatment group at Week 12.

   
   
2. Percentage change from baseline in non-inflammatory lesion counts [ Time Frame: Week 12 ]

   Percent change from baseline in non-inflammatory lesions count in each treatment group at Week 12.

   
   
3. Change from baseline in inflammatory lesion counts [ Time Frame: Week 12 ]

   Absolute change from baseline in inflammatory lesion counts in each treatment group at Week 12.

   
   
4. Change from baseline in non-inflammatory lesion counts [ Time Frame: Week 12 ]

   Absolute change from baseline in non-inflammatory lesion counts in each treatment group at Week 12.

   
   
5. Change from baseline in total lesion counts [ Time Frame: Week 12 ]

   Absolute change from baseline in total lesions counts in each treatment group at Week 12.

   
   
6. Change from baseline in Investigator's Global Assessment (IGA) [ Time Frame: Week 12 ]

   Absolute change from baseline in Investigator's Global Assessment (IGA) in each treatment group at Week 12.

   
   
7. Treatment success rate [ Time Frame: Week 12 ]

   The proportion of subjects in each treatment group achieving "success" at Week 12, with "success" defined as an IGA score of "clear (score=0)" or "almost clear (score=1)"; if IGA score at baseline is 2, success is only achieved if IGA score is 0 at Week 12.

   
   

Other Outcome Measures:

1. Local Adverse Reactions [ Time Frame: Week 2, Week 4, Week 8 and Week 12 ]

   Local Adverse Reactions including erythema, scaling, stinging, burning and pruritus scored by severity

   
   

Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.

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Inclusion Criteria:

• Male or female, aged 12-40 years old
• Diagnosis of Grade II-III acne vulgaris with Pillsbury grading system
• Provide written informed consent if the subject is aged 18 or older. Ages 12-17 should provide written assent and written informed consent from patient's parent or legal guardian.

Exclusion Criteria:

• Known hypersensitivity to adapalene, clindamycin hydrochloride, clindamycin phosphate, lincomycin or any ingredient of the study drug, or of allergic constitution
• Secondary Acne, such as occupational acne and steroid acne
• Has a dermatological condition of the face that could interfere with the clinical evaluations, such as sunburn, psoriasis, seborrheic dermatitis or eczema
• History of Crohn's disease, ulcerative colitis or antibiotic-associated colitis
• History of serious heart disease or hypertension
• Serious liver or kidney disease, AST or ALT more than twice the upper limit of normal, or Cr above normal
• Serious endocrine, hematologic or psychiatric disease
• Known immunocompromised conditions, or require long-term steroids or immunosuppressants
• Females who are pregnant, lactating, or not willing to use effective contraception
• Drug or alcohol abuse
• Used any topical acne treatment within 2 weeks
• Used any systemic retinoid, antibiotic or other acne treatment
• Used any investigational drugs or device within 3 months, or concurrently enrolled in another clinical trial
• Patient who the investigator deemed to be unsuitable for any reason

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03615768

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Lee's Pharmaceutical Limited

Zhaoke (Guangzhou) Ophthalmology Pharmaceutical Ltd.

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Additional relevant MeSH terms:

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