The sun is no friend to your skin. Spending hours soaking up rays can do more than make your skin a few shades darker. It can increase your risk for skin cancer. Show
Squamous cell carcinoma (SCC) is a type of skin cancer that most commonly forms on parts of your body exposed to the sun’s rays. Squamous cell carcinoma is more likely to develop on your arms, legs, face, hands, neck, and lips, but it can also develop inside your mouth or on your genitals. Bowen’s disease, also called squamous cell carcinoma in situ, is the earliest form of SCC. This precancerous spot typically appears as a flat, reddish, scale-like patch on the skin that’s often larger than one inch and grows slowly. In about 5 percent of cases, Bowen’s disease becomes squamous cell carcinoma. Bowen’s disease is most common in older white men. Actinic keratosis (AK) are precancerous growths — often mistaken as sunspots or age spots — that can eventually turn into SCC. These growths may itch and burn, or feel painful when rubbed. In some cases, actinic keratosis also causes dry, scaly lips. Don’t mistake a newly risen area of your skin as a mole or harmless cyst. Squamous cell carcinoma can start as a firm, elevated bump or lump. It then becomes dome-shaped, and it may eventually open, bleed, and scab. In some cases, this bump may grow rapidly. Cancerous skin growths develop much faster than growths caused by other conditions, and they may develop on areas of your skin that are scarred from a previous injury. People of all ages experience pimples or sores on their bodies from time to time. Usually these sores clear up in a few days or a week. A sore that doesn’t heal or go away is a potentially bigger problem. Skin cancer prevents your skin from healing. A patch of skin that doesn’t heal in regular time may be a sign of squamous cell carcinoma. These spots typically bleed easily if bumped or rubbed. Warts and moles are rarely cause to worry. Though they may cause some irritation, most warts and moles are completely harmless. Because squamous cell carcinoma sometimes develops in existing skin lesions, it’s important to monitor moles, warts, or skin lesions for changes. Any observable change should raise a red flag and warrant a trip to the doctor for further examination. The prognosis for SCC depends on a few factors, including:
The sooner SCC is diagnosed, the better. Once found, treatment can begin quickly, which makes a cure more likely. It’s important to treat precancerous lesions, like Bowen’s disease or actinic keratosis, early before they develop into cancer. See your doctor right away if you notice any new or unusual skin lesions. Make regular appointments with your doctor for a skin check. Perform a self-examination once every month. Ask a partner or use a mirror to check places you can’t see, like your back or the top of your head. This is especially important for higher risk individuals, such as those with light skin, blond hair, and light-colored eyes. Anyone who spends prolonged time in the sun unprotected is also at risk. Once you’ve had squamous cell carcinoma, you’re at higher risk for a recurrence, even if the cancer is removed successfully. Take steps to prevent recurrence and always protect your skin from the sun. Avoid direct exposure to sunlight, and wear high-quality sunscreens with a sun protection factor (SPF) of at least 30. No amount of time in the sun is too short for sun damage, so lather on sunscreen even if you’ll only be in the sun for a few minutes. Wearing sun-reflecting clothing, long shirts, or long pants can also prevent sun exposure. Squamous cell cancer (SCC), also known as squamous cell carcinoma, is a type of cancer. It develops in squamous cells, which are the thin, flat cells that make up the outermost layer of your skin. Squamous cells are also found in other parts of your body such as your lungs, mucous membranes, digestive tract, and urinary tract. SCC that forms in your skin is known as cutaneous SCC (cSCC). cSCC develops due to changes in the DNA of squamous cells, which causes them to multiply uncontrollably. It often forms on parts of your skin frequently exposed to sunlight like your face, neck, or arms. Keep reading to learn more about this type of skin cancer, what it looks like, what causes it, and how it’s diagnosed and treated. Cutaneous SCC (cSCC) is a cancer that develops in the squamous cells of your skin. According to the Skin Cancer Foundation, about 1.8 million people in the United States are diagnosed with cSCC each year. It’s the second most common type of skin cancer. Although cSCC isn’t life threatening, it can become dangerous if it goes untreated. When treatment isn’t received quickly, the growths can increase in size and spread to other parts of your body, causing serious complications. People with cSCC often develop scaly, red patches, open sores, or warty growths on their skin. These abnormal growths can develop anywhere, but they’re most often found in areas that receive the most exposure to ultraviolet (UV) radiation, either from sunlight or from tanning beds or lamps. Oral SCC also makes up more than 90 percent of mouth cancers. Lung SCC makes up about 30 percent of a group of lung cancers called non-small cell lung cancer and about 25 percent of lung cancers overall. Here are some examples of what squamous cell carcinoma can look like: Your skin has multiple layers. The outer, protective layer of the skin is known as the epidermis. The epidermis has three main types of cells:
The cells of the epidermis are constantly shedding to make way for fresh, new skin cells. However, when certain genetic changes occur in the DNA of any of these cells, skin cancer can occur. The main types of skin cancer are:
Squamous cell cancerSquamous cells are the cells closest to your skin’s surface, and their purpose is to line your skin. cSCC often develops in areas of the body that are frequently exposed to UV radiation, such as your face, hands, and ears. Basal cell cancerBasal cells sit below the squamous cells, and they’re constantly dividing to form new cells. According to the American Cancer Society, basal cell carcinoma makes up about 80 percent of skin cancers. Like cSCC, basal cell cancer typically develops in areas exposed to UV rays, particularly your face and neck. This type of cancer tends to grow slowly, and it rarely spreads to other parts of your body. However, if basal cell cancer goes untreated, it can eventually spread to your bones and other tissues. MelanomaAlong with basal cells, melanocytes are located in the deepest section of your epidermis. These cells are responsible for producing melanin, the pigment that gives skin its color. When cancer develops in melanocytes, the condition is known as malignant melanoma. Malignant melanoma is less common than squamous cell and basal cancers, but it’s more likely to grow and spread when it’s left untreated. cSCC often occurs in areas exposed to UV radiation, such as your face, ears, and hands. However, it can also appear in your mouth, around your anus, and on your genitals. Symptoms of cSCC can include:
According to the American Academy of Dermatology, cSCC is most commonly red or pink. It can also be:
In your mouth, this cancer can cause:
It’s a good idea to make an appointment with your doctor or dermatologist right away if you notice any symptoms of cSCC or experience a sore or growth that doesn’t heal. An early diagnosis and treatment are critical for preventing complications. cSCC is caused by mutations that occur in squamous cell DNA. These changes cause abnormal cells to multiply out of control. UV radiation is the most common cause of the DNA mutations that lead to cSCC and other skin cancers. Causes of squamous cell cancerMost cases of cSCC are attributed to exposure to UV radiation from sunlight or indoor tanning equipment like tanning lamps and beds. Other potential causes include:
Risk factors for squamous cell cancerRisk factors for cSCC include:
Treatment for cSCC varies. Treatment is based on:
If cSCC is caught early, the condition can usually be successfully treated. It becomes harder to cure once it has spread. Many treatments can be performed as in-office procedures. Treatments may include:
Non-FDA-approved methods for treating squamous cell carcinomaSome doctors may also use laser surgery and topical medications to treat cSCC. However, the Food and Drug Administration has not approved these methods for treating cSCC:
Once cSCC has been treated, it’s critical to attend all follow-up visits with your doctor. cSCC can return, and it’s important to monitor your skin for any precancerous or cancerous areas at least once per month. Your doctor will first perform a physical exam and inspect any abnormal areas for signs of cSCC. They’ll also ask you about your medical history. If cSCC is suspected, your doctor may decide to take a biopsy to confirm the diagnosis. A biopsy usually involves removing a very small portion of the affected skin. The skin sample is then sent to a laboratory for testing. In some cases, your doctor may need to remove a larger part or all of the abnormal growth for testing. Talk with your doctor about any potential scarring or biopsy concerns. After receiving treatment for cSCC, be sure to attend all follow-up visits with your doctor. It’s possible for the cancer to return, so it’s critical to check your skin for any signs of cancer or precancer at least once per month. To help reduce your risk of cSCC, follow these tips when possible:
Early detection of cSCC is key to successful treatment. If cSCC isn’t treated in its early stages, the cancer may spread to other areas of the body, including the lymph nodes and organs. Once this occurs, the condition can be life threatening. People with weakened immune systems due to certain medical conditions, such as HIV, AIDS, or leukemia, have a greater risk of developing more serious forms of cSCC. It’s a good idea to see a doctor right away if you suspect you have any type of skin cancer. What does squamous cell carcinoma look like at first?What does SCC look like? SCCs can appear as scaly red patches, open sores, rough, thickened or wart-like skin, or raised growths with a central depression. At times, SCCs may crust over, itch or bleed. The lesions most commonly arise in sun-exposed areas of the body.
How does squamous cell carcinoma start?Most squamous cell cancers occur on skin that is regularly exposed to sunlight or other ultraviolet radiation. The earliest form of squamous cell cancer is called Bowen disease (or squamous cell carcinoma in situ). This type does not spread to nearby tissues, because it is still in the outermost layer of the skin.
What does the start of squamous cell look like?Squamous cell carcinoma initially appears as a skin-colored or light red nodule, usually with a rough surface. They often resemble warts and sometimes resemble open bruises with raised, crusty edges. The lesions tend to develop slowly and can grow into a large tumor, sometimes with central ulceration.
What can be mistaken for squamous cell carcinoma?Pseudoepitheliomatous hyperplasia (PEH) arises in areas of chronic inflammation and can be mistaken for squamous cell carcinoma, leading to unnecessary removal of more tissue.
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