DEXAMETHASONE+NEOMYCIN+POLYMYXIN B belongs to the class of ocular medications called ‘antibiotics’ to treat inflammation associated with bacterial eye infections. It treats eye infections like conjunctivitis (infected conjunctiva) and chronic anterior uveitis (long-term inflammation inside the front of your eye). It prevents the damage caused by any foreign objects entering the eye, such as chemicals. Show
DEXAMETHASONE+NEOMYCIN+POLYMYXIN B contains Dexamethasone, Neomycin, and Polymyxin B. Dexamethasone is a steroid medicine that inhibits prostaglandins (chemical substances) that cause inflammation and symptoms associated with infection such as redness and irritation. Neomycin and Polymyxin B are antibiotics. They are bactericidal and kill the bacteria by interfering with its growth. You should take this medicine exactly as prescribed by the doctor. The common side-effects of DEXAMETHASONE+NEOMYCIN+POLYMYXIN B are application site burning/stinging sensation, redness, itching, irritation, and blurred vision. These side-effects are usually mild and temporary. However, if any of these side effects persist or get worse, consult your doctor immediately. It is not recommended to take DEXAMETHASONE+NEOMYCIN+POLYMYXIN B if you are allergic to any contents of it. Do not use DEXAMETHASONE+NEOMYCIN+POLYMYXIN B if you have any untreated viral, fungal, or parasitic eye infection and untreated red eye. It is not advised to use in children below 2 years of age, pregnant women, and breastfeeding mothers. It should be used with caution in elderly people. DEXAMETHASONE+NEOMYCIN+POLYMYXIN B may not interact with alcohol. DEXAMETHASONE+NEOMYCIN+POLYMYXIN B may cause blurred vision, which is temporary, so do not drive or operate heavy machinery until your vision is clear. Uses of DEXAMETHASONE+NEOMYCIN+POLYMYXIN BBacterial eye infections Medicinal BenefitsDEXAMETHASONE+NEOMYCIN+POLYMYXIN B is used for short-term treatment of eye inflammation. It is used to treat eye infections such as conjunctivitis (infected conjunctiva) and chronic anterior uveitis (long-term inflammation inside the front of your eye). DEXAMETHASONE+NEOMYCIN+POLYMYXIN B is a combination of steroids and antibiotics. So, it can effectively reduce inflammation and infection. Directions for UseDEXAMETHASONE+NEOMYCIN+POLYMYXIN B is available in the form of eye drops. Eye drops: Wash your hands thoroughly with water before and after use. Take the prescribed amount of dose with the dropper and squeeze out a drop without touching the eye. Wipe any excess liquid with a tissue. Do not wipe or rinse the dropper tip after use. Place the dropper back on the bottle and tighten the cap. Note: Do not touch the tip of the dropper as it may contaminate the contents. Do not place the tip directly into the eye while instilling the drop. If the dropper touches the eye, immediately squeeze two to three drops onto the tissue and wipe the dropper’s tip with saltwater. Discard any unused medicine after completing the course of therapy or within 4 weeks after opening the bottle. StorageStore in a cool and dry place away from sunlight Side Effects of DEXAMETHASONE+NEOMYCIN+POLYMYXIN B
In-Depth Precautions and WarningDrug WarningsDEXAMETHASONE+NEOMYCIN+POLYMYXIN B is available for topical (for eye) use only. It should not be swallowed or injected. Before taking DEXAMETHASONE+NEOMYCIN+POLYMYXIN B, inform your doctor if you have a disorder that causes thinning of the eye tissues. DEXAMETHASONE+NEOMYCIN+POLYMYXIN B may increase the risk of infections in some patients, so inform your doctor if you notice eye pain, redness, or irritation that is persistent. DEXAMETHASONE+NEOMYCIN+POLYMYXIN B may delay healing of your eye wound, and the risk is high if you are taking topical nonsteroidal anti-inflammatory drugs (NSAIDs). Prolonged use of DEXAMETHASONE+NEOMYCIN+POLYMYXIN B may cause increased pressure in the eye, cataract (clouding of the eye) formation, and increased risk of infections, especially in diabetic patients. The risk for increased pressure in the eye is also high in children when used for the long term. DEXAMETHASONE+NEOMYCIN+POLYMYXIN B may cause Cushing’s syndrome, characterized by swelling and weight gain around the trunk and face. DEXAMETHASONE+NEOMYCIN+POLYMYXIN B may suppress adrenal gland function when used for longer periods. The risk is high in children and individuals taking medicines to treat HIV, such as ritonavir and cobicistat. Consult your doctor if you notice persistent blurred vision or visual disturbances. DEXAMETHASONE+NEOMYCIN+POLYMYXIN B contains benzalkonium chloride (a preservative), which may cause eye irritation, especially in patients with dry eyes or disorders of the cornea. So, if you experience a persistent stinging sensation or pain in the eye after taking this medicine, inform your doctor immediately. Benzalkonium may also react with contact lenses and change the color of lenses. Drug InteractionsDrug-Drug Interactions: DEXAMETHASONE+NEOMYCIN+POLYMYXIN B may interact with topical nonsteroidal anti-inflammatory drugs or NSAIDs (diclofenac and ketorolac), medicines used to treat HIV (ritonavir and cobicistat), medicines used to treat diabetes (insulin, metformin, and chlorpropamide, etc.). Drug-Food Interactions: No interactions found. Drug-Disease Interactions: DEXAMETHASONE+NEOMYCIN+POLYMYXIN B should be used with caution in patients with untreated viral, fungal, or parasitic eye infection, untreated red-eye, diabetes, corneal disorders, and glaucoma (increased pressure in the eye). Safety Advice
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Patients ConcernDisease/Condition GlossaryBacterial eye infections: These are the common eye problems seen in a primary care setting. The common bacterial eye infections are conjunctivitis, stye, or keratitis. Conjunctivitis (pink eye) is the inflammation or infection of the conjunctiva (white part of the eye) and the inner eyelid. It is a highly contagious infection that spread by secretions of the eye. Symptoms include redness, itchy, and discharge or crusting around the eye. A stye, a bump on the eyelid, is also a common eye condition. Keratitis, inflammation of the cornea, occurs due to frequent contact lenses, injury, diabetes, or surgery. Chronic anterior uveitis is the long-term inflammation inside the front of your eye. FAQsHow long does it take neomycin and polymyxin B to work?Hydrocortisone - neomycin - polymyxin B ear drops are used to treat certain bacterial infections of the outer ear canal. This medication should start to work within 48 hours.
What infections does neomycin treat?Neomycin, an antibiotic, is used to prevent or treat skin infections caused by bacteria. It is not effective against fungal or viral infections. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.
What happens if you put neomycin in your eye?Stinging/burning of the eyes for 1 to 2 minutes or temporary blurred vision may occur when this medication is applied. If any of these effects last or get worse, tell your doctor or pharmacist promptly.
How long does it take for neomycin to work?Your symptoms should begin to improve during the first few days of treatment with neomycin, polymyxin, and hydrocortisone otic combination. If your symptoms do not improve after one week or get worse, call your doctor.
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