Why no caffeine before allergy test

Antihistamines will affect the results of skin prick tests and need to be stopped before the testing is completed in order to get accurate results.

  • If you are taking an oral antihistamine that is not listed stop the medicine 5 days before your appointment. If you are not sure if the medicine you are taking is an antihistamine, ask your doctor. Some over-the-counter cold and flu medications contain an antihistamine, so be sure to read labels carefully.

  • Local antihistamines (Examples: azelastine (nose or eye), olopatadine (eye)) should be stopped 2 days prior to your appointment. 

  • ​The following reflux medications should be stopped 2 days prior to your appointment.  If you are on a different reflux medication, it does not need to be stopped.
    • Axid® (nizatidine)

    • Pepcid® (famotidine)

    • Tagamet® (cimetadine)

    • Zantac® (ranitidine)

  • Some psychiatric medications, including tricyclic antidepressants (eg. amitriptyline doxepin, nortriptyline), can also affect the results of your skin testing. Let your doctor know if you are on any antidepressants or sleep aides before your test, but do not stop them without consulting the prescribing doctor.

  • It is OK to continue to take all your other medicine as you usually do. Inhaled steroids used for asthma,  nasal steroids (eg Nasacort, Flonase, Nasonex) as well as Singulair (montelukast) will not interfere with the results of your skin testing and may be continued.  

  • High dose oral steroids may effect skin test results, but do not stop any oral steroid medications unless advised by your physician 

  • ​Do not apply lotions or creams to your back the day of your appointment.

Very Important! Please Read!

As a general rule all oral allergy, cold and sinus medications need to be stopped 5 days prior to skin testing.

This includes over the counter medications and herbal supplement.

Other classes of medications that may interfere with skin testing:

  • Sleep Medications (e.g., Tylenol PM)
  • Tricyclic Anti Depressants
  • Anti Anxiety Medications
  • Stomach Acid Medications
  • Prednisone (chronic use*)

*Chronic use = >10mg/day for more than 2 weeks.
If used chronically – off 2 weeks prior to testing. Ask your MD how to taper off.
If not chronic use – no need to go off of it.

It is okay to continue:

  • Asthma Inhalers
  • Pseudoephedrine
  • Guaifenesin
  • Dextromethorphan
  • Nasal Sprays (Except Astelin, Patanase, Astepro, Dymista)
  • Antibiotics
  • Oral Contraceptives

Specific Medications

The following is a list of medications that needs to be stopped before skin testing in order to obtain accurate results. We understand that some of these may be difficult to stop. If you have concerns about stopping any of the following medications please discuss this with your physician’s office and let us know.

If you are on an allergy medication and do not see it on the list please call our office to be sure it is okay to continue taking it.

Medications to STOP 7-14 days prior to Testing*

  • Amitryptyline (Elavil)
  • Clomipramine (Anafranil)
  • Doxepin (Sinequnan)
  • Imipramine (Tofranil)
  • Trimipramine (Surmontil)
  • Amoxapine (Asendin)
  • Desipramine (Nupramin)
  • Nortiptyline (Pamelor, Aventyl)
  • Protriptyline (Vivactil)
  • Maprotiline (Ludiomil)
  • Mirtazapine (Remeron)
  • Trazadone (Desyrel)
  • Nefazadone (Serzone)
  • Astelin (Azelastin)/Astepro
  • Dymista Patanase (Olopatidine)

*Please consult with your physician before stopping any of these medications if you take them on a regular basis.

Medications to STOP 5-7 days prior to Testing

  • Claritin (Loratidine)
  • Allegra (Fexofenadine)
  • Clarinex (Desloratidine)
  • Periactin (Cyproheptadine)
  • Quercetin

Medications to STOP 3-4 days prior to Testing

  • Actifed, Dimetapp (Brompheniramine)
  • Atarax, Vistaril (Hydroxyzine)
  • Benadryl (Diphenhydramine)
  • Chlortrimetron (Chlorpheniramine)
  • Dexchlorpheniamine (Polaramine)
  • Phenergan (Promenthazine)
  • Vitamin C
  • All allergy eye drops OTC and RX (as tolerated)
  • Zyrtec (Cetirazine)
  • Compazine (Prochlorperazine
  • Xyzal (Levocetirazine)
  • Tylenol PM
  • Advil PM
  • Tavist, Antihist (Clemastine)
  • Nettle (herbal medication)

Medications to Stop the day before Testing

  • Singulair (Montelukast)
  • Zyflo (Zileuton)
  • Accolate (Zafirleukast)
  • Reglan (Metoclopramide)
  • Prevacid
  • Ranitidine (Zantac)
  • Cimetidine (Tagamet)
  • Famotidine (Pepcid) & Pepcid Complete
  • Nizatidine (Axid)
  • ALL.35 Rev 04/14
  • Medications to Stop the day before Testing
  • Protonix
  • Prilosec (Omeprazole)
  • Nexium
  • Omeprazole
  • Kapidex
  • Aciphex
  • Zegerid
  • Dexilant (dexlansoprazole)

Does caffeine interfere with allergy testing?

Do not drink any caffeinated beverages prior to the test. Shower in the morning. Do not apply any perfumes, colognes, or scented products. Do not smoke or use tobacco products for 4 hours prior to the testing appointment.

Is it OK to drink coffee before an allergy test?

TWO DAYS: Prior to testing, STOP all alcohol, chocolate, coffee and all other caffeine products (i.e. Pepsi, Coke, Mountain dew, etc). day of your test, and wear loose-fitting clothes so your arms can be easily accessed.

What can mess up an allergy test?

Do not take Claritin, Clarinex, Zyrtec, Xyzal, or Allegra for 7 days prior to the allergy test. Do not take over the counter antihistamines (Benadryl, cold & sinus medications, sleep aids such as Tylenol PM) 7 days before the test.

Can I drink tea before allergy testing?

Check with your Primary Physician before stopping any medications. No herbal supplements or herbal teas/Green tea 5-7 days preceding the allergy test.